The health facts contained herein is furnished for instructional purposes only and is not intended to replace discussions with a healthcare service provider. All selections pertaining to affected person care must be produced that has a healthcare service provider, taking into consideration the exclusive attributes in the affected person. This website is intended for people of The us only. The merchandise talked over herein could possibly have various product or service labeling in different countries. This Web page contains info associated with numerous health care ailments and treatment method.

For oral dosage variety (tablets): For narcolepsy or obstructive sleep apnea/hypopnea syndrome: Grown ups and youngsters seventeen yrs of age and older—two hundred milligrams (mg) when daily, each morning. Your health practitioner might boost your dose as needed. Adolescents and youngsters young than seventeen years of age—Use and dose must be based on your health practitioner.

Clopidogrel efficacy could possibly be lowered by medication that inhibit CYP2C19. Inhibition of platelet aggregation by clopidogrel is entirely as a consequence of an active metabolite. Clopidogrel is metabolized to this active metabolite partly by CYP2C19. .

Modafinil might be routine-forming. Never share Provigil with An additional individual, Specifically an individual using a heritage of drug abuse or habit. Maintain the medication in a location exactly where Many others can't reach it. Marketing or making a gift of this medicine is against the law.

Belzutifan is usually a CYP2C19 substrate. Coadministration with CYP2C19 inhibitors could increase incidence or severity of adverse consequences. Watch for anemia and hypoxia and reduce belzutifan dose as suggested.

saquinavir will boost the level or effect of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.

Stay away from or substitute Yet another drug for these medicines when probable. Examine for lack of therapeutic result if medication have to be coadministered. Modify dose In keeping with prescribing information and facts if wanted.

Sufferers needs to be suggested to speak with their Health care service provider promptly if they expertise a rash or any allergic reaction, depression, anxiousness, or signs of psychosis or mania.

The success of steroidal contraceptives can be decreased when applied with PROVIGIL and for a single thirty day period following discontinuation of therapy. Choice or concomitant methods of contraception are advised for people using steroidal contraceptives (e.

tazemetostat will reduce the extent or effect of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.

Stiripentol can be a CYP3A4 inhibitor and website inducer. Watch CYP3A4 substrates coadministered with stiripentol for enhanced or reduced outcomes. CYP3A4 substrates might demand dosage adjustment.

A 2019 review performed to the potential nootropic results of modafinil in healthier, non-slumber-deprived individuals exposed the next:[248] a) although experiments utilizing standard tests paradigms demonstrated that modafinil improves government functionality, only half of those scientific tests confirmed advancements in notice, learning, and memory, having a couple of scientific studies even reporting impairments in divergent Innovative imagining; b) modafinil exhibited smaller amounts of improvement in awareness, govt features, and Mastering qualities; c) no sizeable Negative effects or mood alterations have been noticed; d) the readily available proof confirmed minimal proof for modafinil like a cognitive enhancer outside of its use for sleep-deprived populations.

efavirenz will lessen the level or impact of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

Halting abruptly could potentially cause significant complications and could cause you to acquire seizures much more generally. Before using FYCOMPA, convey to your healthcare supplier about your whole healthcare problems, together with in the event you: